PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE AERIAL PART OF ALYSICARPUS OVALIFOLIUS Schumach & Thonn FAMILY: FABACEAE
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
Alysicarpus ovalifolius (Schum.&Thonn) Family: Fabaceae is a protein rich fodder plant that is widely distributed across Africa, Asia and Australia and medicinally used to treat cough and wounds. Recently, it has been reported to be used in the Northern part of Nigeria as tea by commercial motor cycle riders popularly known as “okada riders”, labourers and young people .The dried powder of the plant was initially defatted with petroleum ether, the marc was further subjected to extraction with methanol and partitioning with petroleum ether, ethyl acetate and n-butanol. The preliminary phytochemical screening shows the presence of steroids, triterpenes and cardiac glycosides in the petroleum ether fraction while cardiac glycosides, saponins, steroids, triterpenes and flavonoids are present in the methanolic extract. The n-butanol fraction was subjected to column chromatography, gel filtration and preparative thin layer chromatography to yield two compounds coded D7 and E17. D7 was characterized as a glycosidic flavone (3,5-dihydroxy-4¹-methoxy-7-O-βglycosyl flavone,(C19H22O10) and E17 was characterized as 3 β –cholest-5-ene-3-diol using chemical tests and spectral analysis (1H-NMR) and extensive literature review. The pharmacological studies carried out on the extract to show it has central nervous stimulant activity are, the drug (diazepam) induced- sleep in mice and the hole-board experiment. The acute toxicity test of the extract was also carried out. The diazepam induced-sleep study showed decreased onset of sleep and and increase in the duration of sleep while the hole board suggest that the n-butanol fraction of methanolic extract contain constituents which may possess central nervous system stimulant activity as seen in the exploratory behavior of the mice. It can be said that the plant Alysicarpus ovalifolius (Schum&Thonn) possess some central nervous stimulant activity and therefore the plant could be exploited for its stimulant property
Related Project Materials
AN ASSESSMENT OF STRATEGIC MANAGEMENT AND ITS THE EFFECT ON ORGANIZATIONS PERFORMANCE (A CASE STUDY OF KRISORAL GROUP OF COMPANIES LIMITED ONITSHA)
BACKGROUND OF THE STUDY
The economic environment is rapidly changing, with phenomena...
EFFECT OF CLASS SIZE ON STUDENTS’ ACADEMIC PERFORMANCE IN SOCIAL STUDIES
Background to the Study
According to Adeyemi and Adu (2010), it is widely accepted that education is on...
THE ROLE OF EFFECTIVE ADMINISTRATION IN THE RAPID SOCIAL-ECONOMIC TRANSFORMATION OF NIGERIA
ABSTRACT
This study was carried out to examine the role of effective administration in the rapid social-eco...
THE NEED FOR EFFECTIVE MANAGEMENT: AN EXAMINATION OF ORGANIZATIONAL POLICIES AND PROCEDURES (A CASE STUDY OF UNION BANK OF NIGERIA PLC)
ABSTRACT
In all business enterprise the need for effective management: an examination of organizational policies an...
The Role of Music and Movement in Early Childhood Development
Abstract: This study explores the role of music and movement in early childhood development, aiming to understand how rhythmic act...
BENEFITS OF EARLY CHILDHOOD EDUCATION IN FOSTERING ENVIRONMENTAL STEWARDSHIP
ABSTRACT: This research investigated the benefits of early childhood education in fostering environmental stewardship among young children. The obj...
FACTORS INFLUENCING UTILIZATION OF PREVENTION OF MOTHER TO CHILD TRANSMISSION (PMTCT) SERVICES AMONG PREGNANT WOMEN
Background of the Study
The universality of harmful beliefs and subsequent negative attitudes towards t...
INFLUENCE OF EARLY CHILDHOOD EDUCATION ON DIETARY DIVERSITY
ABSTRACT: This study examines the influence of early childhood education on dietary diversity among young children. Early exposure to dietary...
AN ASSESSMENT OF PHOTOGRAPHS AND CARTOONS AS COMMUNICATION INSTRUMENTS
ABSTRACT
Photographs in news stories can stimulate opinion change, either making a reader love the good advertised, or m...
THE EFFECT OF MODERNIZATION ON TRADITIONAL MARRIAGE
ABSTRACT
This study investigated effect of modernization on traditional marriage in Ibarapa North Local...
